Full time, Full Time
MUSC Health
Charleston, SC
Job Description Summary A Research Specialist III is sought for studies aimed at characterizing peptide-based nanotubes for drug delivery across the blood-brain barrier (BBB). These nanotubes represent a highly novel drug delivery platform with applications across multiple diseases. We seek a highly motivated individual capable of working independently and developing our research program. Tasks will involve but are not limited to the following: preparing nanotubes of defined length and loading them with small molecule drugs or biologics (monoclonal antibodies) for use in in vitro blood-brain barrier (BBB) transit studies, and for BBB transit studies in mice. Mouse studies will be carried out in the Small Animal Imaging Shared Resource at Hollings Cancer Center. These studies will require expertise in confocal microscopy for ex vivo localization of fluorescently tagged nanotubes. Work will include executing data analysis on new software, cell culture, microscopy, brain tissue...